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Private Sector
YHEC offers a range of services to private sector clients.
- Economic Evaluations and HTA
YHEC has expertise in undertaking health technology assessment and economic evaluations on a range of healthcare interventions.
- Global HTA Models
YHEC specialises in the development of global models for purposes of health technology assessment. Such models have been carried out in a wide range of disease areas, and have been submitted to NICE, the SMC and the AWMSG.
- Early Modelling
Economic evaluations are increasingly used as tools to inform decision-makers about the cost-effectiveness of health technologies. Such evaluations are often undertaken during the late stages of the technology development (i.e. around the time of product launch or, in some cases, post-launch).
- Budget Impact Models
In many cases, economic evaluations are designed to show the value for money of a new technology. However, many payers, particularly those at a local level of decision making, are interested in the affordability of an intervention.
- Burden of Illness Models
YHEC undertakes burden of illness studies for any particular disease area or indication. Such studies are aimed at identifying the overall impact of an illness, including its economic cost to society, and the health consequences of that disease.
- Model Critique and Validation
Our experienced modelling team have designed a systematic approach to critiquing existing economic models for purposes such as HTA submission.
- Model Adaptation
YHEC has extensive experience in writing economic submissions to the UK health technology assessment bodies, NICE, SMC and the AWMSG. As such, we provide a service to update and adapt existing models to be generalisable to the UK setting.
- Information Services
Information is key to high quality research. Identifying and managing research evidence efficiently within projects is one of our strengths. We offer information services to support research in a range of topic areas. We also have expertise in information retrieval research and information skills training.
- Reviewing Services
YHEC offers a range of reviewing services from scoping reviews and rapid evidence reviews, through to systematic reviews to inform reimbursement decisions for bodies such as NICE. We also undertake reviews to identify research gaps, to inform the development of economic models and to summarise health-related quality of life.
Some of our recent publications are:
Glanville, J, Kendrick A, McNally R, Campbell J, Hobbs FD. Research output on primary care in Australia, Canada, Germany, the Netherlands, the United Kingdom, and the United States: bibliometric analysis. BMJ 2011; 342: d1028.  Hutton, J. Mixed palette Pharmaceutical Marketing Update 2010; July/August : 24-26. Brown A, Craig J. Oxford Diabetes Library: Heart Disease and Diabetes Health economics of treating heart disease in diabetes In: Fisher M editors. Oxford: OUP 2009. Stamuli E, Kruger J, Hutton J. Cost-effectiveness of ultrasound elastography in the assessment of liver fibrosis Centre for Evidence-Based Purchasing Economic Report CEP08053 2009; February. Ritchie K, Bradbury I, Craig J, Eastgate J, Foster L, Kohli H, Iqbal K, MacPherson K, McCarthy T, McIntosh H, Nic Lochlainn E, Reid M, Taylor J. The clinical and cost effectiveness of screening for meticillin-resistant staphylococcus aureus (MRSA) (HTA report 9) In: Edinburgh: NHS Quality Improvement Scotland 2007 Available from: The clinical and cost effectiveness of screening for meticillin-resistant staphylococcus aureus (MRSA) (HTA report 9) Mauskopf JA, Sullivan SD, Annemans L, Caro J, Mullins CD, Nuijten M, Orlewska E, Tam T, Trueman P, Watkins J, Wilson A. Principles of good practice for budget impact analysis Report of the ISPOR Task Force on Good Research Practices - Budget Impact Analysis 2006; September. Téot L, Cherry G, Denis C, Dervaux B, Duncan G, Gottrup F, Harding K, Kerihuel JC, Lautenberg A, Mani R, Meaume S, Messina R, Morris S, Orsted H, Pavlovic M, Peter R, Ricci E, Sibbald G, Sussmann G, Trueman P, World Union of Wound Healing Societies. Reimbursement of dressings: a WUWHS statement International Wound Journal 2006; 3(4) December: 296-301. Williams C, Brunskill S, Altman D, Briggs A, Campbell H, Clarke M, Glanville J, Gray A, Harris A, Johnston K, Lodge M. Cost-effectiveness of using prognostic information to select women with breast cancer for adjuvant systemic therapy Health Technology Assessment 2006; 10(34): 1-222. Hutton J. Health policy and economics Discussion of chapter 3: eliciting equity-efficiency trade-offs in health In: Smith PC, Ginnelly L, Sculpher M editors. Maidenhead: Open University Press 2005. Spencer A, Chilton SM, Covey J, Taylor MJ. Testing the internal consistency of the lottery equivalent method using health outcomes: a comment to Oliver Health Economics 2005; 14: 161-167. Craig, J, Bradbury I, Collinson P, Emslie C, Findlay I, Hunt K, Kohli H, Kulkarni U, Macpherson K, Riches E, Single A, Tochel C. The organisation of troponin testing services in acute coronary syndromes (HTA report 4) In: Edinburgh: NHS Quality Improvement Scotland 2004 Available from: The organisation of troponin testing services in acute coronary syndromes (HTA report 4) Bagust A, Shearer A, Schoeffski O, Reitberger U, Goertz A, Behrens M. Cost-effectiveness in Germany of rosiglitazone-metformin combination in type 2 diabetes Diabetologia 2003; 46(Suppl 2): A444. Gordois A, Scuffham PA, Shearer A, Oglesby A. The costs and consequences of peripheral neuropathy in the UK The Diabetic Foot 2003; 6(1): 30-37. Gordois A, Scuffham PA, Shearer A, Oglesby A. The health care costs of diabetic nephropathy in the United Kingdom and the United States Diabetes 2003; 52(Suppl 1): A185-186. Slattery J, Chick J, Cochrane M, Craig J, Godfrey C, Kohli H, Macpherson K, Parrott S, Quinn S, Single A, Tochel C, Watson H. Prevention of relapse in alcohol dependence In: Edinburgh: NHS Quality Improvement Scotland 2003 Available from: Prevention of relapse in alcohol dependence Scuffham PA, Taylor MJ. Economics and decisions to end life: van Acht and Stooker revisited Applied Health Economics and Health Policy 2002; 1(3): 123-128.
Some of our recent presentations are:
. Cost-effectiveness of meal replacement products in weight control European Congress on Obesity, Prague (May 26-29 2004) 2004 Beale SJ, Tatlock SR, Wheeler K, Ryan J. Telehealth - Initial Users' Views and Impact on Healthcare Resource Use ISPOR 13th Annual European Congress, Prague, 2010 2010 Craig JA, Saxby RC. Economic Evaluation of HeartWare LVAS in the Support of End-Stage Heart Failure in the UK ISPOR 14th Annual European Congress, Madrid, 2011 Drummond M, Nixon J, Boulenger S, Ulmann P, Glanville J, de Pouvourville G. The European Network of Health Economic Evaluation Databases (EURO NHEED) project First Hull-York Medical School Research Conference, Hull (February 2004) 2004 Taylor M, Lewis L, Lebmeier M, Wang Q. An Economic Evaluation of Dasatinib for the Treatment of Imatinib Resistant Patients with Advanced Phase Chronic Myelogenous Leukaemia ISPOR 16th Annual International Meeting (May 21-25, 2011) Baltimore, MD, USA 2011 Taylor M, Lewis L, Lebmeier M, Wang Q. An Economic Evaluation of Dasatinib for the Treatment of Imatinib Resistant Patients with Chronic Myelognous Leukaemia ISPOR 16th Annual International Meeting (May 21-25, 2011) Baltimore, MD, USA 2011 Taylor M, Trueman P et al. Economic benefits of achieving clinical and radiologic remission with etanercept in patients with rheumatoid arthritis American College of Rheumatology Annual Meeting, San Diego (November 2005) 2005 Taylor MJ. The economics of vaccine interventions European ISPOR Conference, Paris (2009) 2009 Taylor MJ, Minda K. An economic evaluation of dasatinib for the treatment of imatinib-resistant patients with chronic myelogenous leukaemia ISPOR European Conference, Dublin (October 2007) 2007 Taylor MJ, Minda K, Ray S et al. Economic evaluation of dasatinib (Sprycel ®) as a treatment for chronic phase chronic myeloid leukaemia in Scotland ISPOR European Conference, Dublin (October 2007) 2007 Taylor MJ, Saxby R. International preferences for health care systems: a discrete choice experiment approach. Health Economics, Management and Policy Conference, Athens, Greece (2009) 2009 Taylor MJ, Saxby RC. Early modelling: methods in the economic analysis of pre-phase II products European ISPOR Conference, Paris (2009) 2009 Taylor MJ, Whitehead SJ, Chilton S. Accounting for initial disease severity when measuring health gains 72nd Health Economics Study Group Meeting, University of East Anglia (January 2008) 2008 Trueman P. The burden of pressure ulcers to the NHS and the potential impact of VAC therapy Wounds UK, Harrogate (November 2005) 2005
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